Noni juice is derived from the fruit of the Morinda citrifolia tree indigenous to Southeast Asia and Australasia. It has been promoted, illegally in several cases, as a cure for a number of human diseases. However, there is no evidence to support any claims of therapeutic benefit. (NOH-nee) Morinda citrifolia. A tropical shrub. An extract from the fruit is being studied as a treatment for cancer, and extracts from the fruit, leaves, or roots have been used in some cultures to treat other diseases. Also called Morinda citrifolia. Human intervention studies also indicate that noni juice may improve joint health, increase physical endurance, increase immune activity, inhibit glycation of proteins, aid weight management, help maintain bone health in women, help maintain normal blood pressure, and improve gum health.