Tretiva 40mg isotretinoin capsules are used to treat severe acne that hasn't responded to other treatments. Isotretinoin is a powerful medication that reduces the size and activity of oil glands in the skin, which helps to prevent acne outbreaks. Each capsule contains 40 milligrams of isotretinoin, and the typical course lasts several months, with dosage adjusted based on individual needs. Common side effects include dry skin, lips, and eyes, and more serious effects can involve mood changes or liver issues. It’s important to follow your doctor’s instructions carefully, use effective contraception to prevent pregnancy (as isotretinoin can cause birth defects), and have regular check-ups while on this medication.